Long hours, hard training and high-stakes decisions demand a mind that stays switched on. ALPHA GPC delivers 500 mg of Alpha-GPC 50%, providing 250 mg of active Alpha-GPC to supply choline, an essential nutrient involved in acetylcholine production and normal cognitive function. Designed for ambitious professionals, entrepreneurs and athletes, it provides targeted nutritional support for focus, mental performance and the cognitive demands of high-pressure, high-output lifestyles.

Alpha-GPC is a choline compound. The body uses choline to make acetylcholine, a neurotransmitter involved in attention, learning and memory processes, so Alpha-GPC supports normal cognitive function and helps you stay focused through demanding work. It carries about 40% choline by weight, which is why a useful serving fits into a single capsule.

The label states two figures separately: the concentration of the raw material and the 250 mg of Alpha-GPC delivered in each capsule. A concentration on its own does not tell you what reaches you, so both are declared, and Alpha-GPC is the only active ingredient, with no proprietary blend.

Alpha-GPC is made for healthy adults aged 18 and over who run long, cognitively demanding days, such as business owners, executives and professionals who need sustained attention, and for athletes and people who train hard. The standard serving is one capsule daily, with a two-capsule enhanced serving for heavier days. Contains Alpha-GPC — account for total daily intake if combining.

The following describes published research on the ingredient. It is not a claim about this specific product.

Studies suggest Alpha-GPC raises circulating choline at a serving that matches this product. Marcus and colleagues (2017) gave 48 healthy college-aged men 250 mg or 500 mg of Alpha-GPC a day for seven days. Serum free choline rose in both Alpha-GPC groups compared with placebo, and the groups differed in countermovement jump velocity and power, with the 250 mg group showing the largest improvement. The same study found no difference on isometric strength tests or on a psychomotor vigilance test of reaction time.

Research indicates further effects at doses above one capsule. Bellar and colleagues (2015) gave 13 college-aged men 600 mg a day for six days in a crossover trial and reported a greater change in lower-body peak force on an isometric mid-thigh pull than with placebo, while the upper-body change did not reach statistical significance; 600 mg is more than twice this product's standard serving. Tamura and colleagues (2021) gave 39 healthy adults either 400 mg a day or a placebo for two weeks and reported higher self-reported motivation in the Alpha-GPC group; 400 mg sits between the one- and two-capsule servings. The evidence is mixed overall, and Bellar's team noted that studies vary widely in dose (200 to 600 mg) and timing (30 to 90 minutes before activity), which may explain the inconsistent findings.

Alpha-GPC compared with citicoline. Both supply choline. Alpha-GPC carries about 40% choline by weight and is a direct route toward acetylcholine, while citicoline (CDP-choline) carries about 18% choline and also supplies cytidine, which the body uses in phospholipid synthesis. They are different molecules rather than stronger and weaker versions of one ingredient, and for the most choline per milligram, Alpha-GPC is the more concentrated source.

Alpha-GPC compared with L-Theanine. They are different ingredients that do different jobs. Alpha-GPC is a choline source used to support cognitive function, while L-Theanine is an amino acid found in tea leaves and chosen for a calm, focused state. They share no active ingredient, so they can be used together, and MitoGenix declares each one separately.

Key Benefits

• Supports Cognitive Function: Supplies choline for acetylcholine, the neurotransmitter involved in attention, learning and memory processes.
• Built for Demanding Days: Helps you maintain focus through long, cognitively demanding work and hard training days.
• Declared 250 mg Dose: One capsule provides 250 mg of Alpha-GPC, with the raw material concentration stated separately on the label.
• Choline-Dense Form: About 40% choline by weight, so a useful amount of choline fits into a single capsule.
• Single Active Ingredient: Alpha-GPC is the only active in the capsule, with no proprietary blend.

Common Questions

What does Alpha-GPC do?
Alpha-GPC is a choline compound. The body uses choline to make acetylcholine, a neurotransmitter involved in attention, learning and memory processes, so Alpha-GPC supports normal cognitive function in healthy adults. MitoGenix Alpha-GPC provides a declared 250 mg per capsule.

How much Alpha-GPC should I take?
The standard serving is one capsule daily, providing 250 mg of Alpha-GPC. The enhanced serving is two capsules daily for higher workload or greater body mass. Do not exceed two capsules a day, and count Alpha-GPC from any other product you take.

When is the best time to take Alpha-GPC?
The label directs one capsule daily with no set time, and it can be taken with or without food. It suits the morning or the time before a demanding block of work or training, and studies on physical output gave it 30 to 60 minutes before exercise.

How long does Alpha-GPC take to work?
Alpha-GPC is a daily nutrient rather than a fast-acting product, so no set timeline applies. Studies have used single doses given 30 to 60 minutes before exercise as well as daily use for one to two weeks, with mixed results. Take it consistently as directed.

Can Alpha-GPC support focus and concentration?
Alpha-GPC supplies choline for acetylcholine, a neurotransmitter involved in attention, which is why it is chosen for demanding workdays. Research in healthy adults is mixed and depends on the dose, so MitoGenix states a clear 250 mg per capsule rather than promising a result.

Is Alpha-GPC safe to take every day?
Yes, MitoGenix Alpha-GPC is directed for daily use at one capsule, or two on the enhanced serving. Do not exceed the recommended dose. It is not intended for anyone under 18 or for pregnant or breastfeeding mothers, and anyone with a known medical condition should consult a healthcare professional first.

What are the side effects of Alpha-GPC?
Alpha-GPC is generally well tolerated. Possible side effects include stomach upset, heartburn, headache and restlessness, and they are more likely at higher doses. Take no more than the recommended dose, and discontinue use if any adverse reactions occur.

Alpha-GPC vs citicoline: which should I choose?
Alpha-GPC carries about 40% choline by weight and is a direct route to acetylcholine. Citicoline carries about 18% choline and also supplies cytidine. If you want more choline per milligram, choose Alpha-GPC; MitoGenix declares 250 mg per capsule.

Can I stack Alpha-GPC with other nootropics?
Yes, and a single-ingredient product makes stacking simple because every dose is declared. MitoGenix Alpha-GPC pairs easily with MitoGenix L-Theanine. Mito-Focus Xtreme already contains Alpha-GPC, so account for total daily intake if combining, and do not exceed either label's dose.

Can I take Alpha-GPC with coffee?
The label sets no restriction on coffee. MitoGenix Alpha-GPC has one active ingredient, Alpha-GPC, so your caffeine intake stays a separate choice. If you are sensitive to caffeine or use other stimulating products, keep your total intake in check, and discontinue use if any adverse reactions occur.

Can I take Alpha-GPC with prescription medication?
Alpha-GPC works through acetylcholine, so medicines that act on the same system could interact with it. Speak to a healthcare professional or pharmacist before combining MitoGenix Alpha-GPC with any prescription medication, and tell them about every other supplement you take.

What makes a good quality Alpha-GPC supplement?
Look for two separate declarations: the raw material concentration and the amount delivered. MitoGenix Alpha-GPC declares ALPHA-GPC 50% delivering 250 mg per capsule, with no proprietary blend, and it is independently tested for identity and purity.

CAUTION: Store in a cool, dry place or below 25°C. Keep out of reach of children. Do not exceed the recommended dose. Not intended for children under 18 years, or pregnant or breastfeeding mothers. Individuals with a known medical condition should consult a healthcare professional before using this health supplement. Discontinue use if any adverse reactions occur.

See the full MitoGenix supplement range, or pair Alpha-GPC with L-Theanine as part of a daily stack.

SAHPRA DISCLAIMER: This unregistered medicine has not been evaluated by SAHPRA for its quality, safety or intended use. Health supplements are intended only to complement health or supplement your diet. This product is not intended to diagnose, treat, cure or prevent any disease.